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Medication Guide
Full Prescribing Information
FDA-approved for the treatment of Moderate to Severe Plaque Psoriasis
Hello {FirstName},

Welcome to the BIMZELX Xperience program!

We’re excited your BIMZELX journey has begun. In about 4 weeks after receiving your first BIMZELX dose, you’ll receive an email with a link to your BIMZELX Xperience survey. Here’s what happens next:
Complete the short, eight-question survey
Click “Submit” and you’re done!
Feedback will automatically be sent to your healthcare provider
Be sure to also discuss your progress with your provider at your next visit, as communication helps inform the next steps in your treatment journey.

If you have any questions, concerns, or would like to share more information about your BIMZELX treatment or your psoriasis, please contact your healthcare provider.

Congratulations on your decision to participate in the BIMZELX Xperience, and for taking an active role in your psoriasis treatment journey. Welcome to the program.

If you wish to opt out of the BIMZELX Xperience program, you may do so at any time by informing your healthcare provider.

Please see Important Safety Information below as well as a link to the full Prescribing Information.
Use for BIMZELX
BIMZELX is a prescription medicine used to treat moderate to severe plaque psoriasis in adults who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet light alone or with pills (phototherapy).
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about BIMZELX® (bimekizumab-bkzx)?
BIMZELX is a medicine that affects your immune system. BIMZELX may increase your risk of having serious side effects, including:
Suicidal thoughts and behavior have happened in some people treated with BIMZELX. Get medical help right away or call the National Suicide and Crisis Lifeline at 988 if you, your caregiver or your family member notice in you any of the following symptoms:
new or worsening depression or anxiety
thoughts of suicide, dying, or hurting yourself
changes in behavior or mood
acting on dangerous impulses
attempt to commit suicide
Infections. BIMZELX is a medicine that may lower the ability of your immune system to fight infections and may increase your risk of infections.
Your healthcare provider should check you for infections and tuberculosis (TB) before starting treatment with BIMZELX.
If your healthcare provider feels you are at risk for TB, you may be treated with medicine for TB before you begin treatment with BIMZELX and during your treatment.
Your doctor should watch you closely for signs and symptoms of TB during and after treatment with BIMZELX. Do not take BIMZELX if you have an active TB infection.
Before starting BIMZELX, tell your healthcare provider if you:
are being treated for an infection
have an infection that does not go away or that keeps coming back.
have TB or have been in close contact with someone with TB.
think you have an infection or have symptoms of an infection such as:
fever, sweats, or chills
muscle aches
cough
shortness of breath
blood in your phlegm
weight loss
warm, red, or painful skin or sores on your body different from your psoriasis
diarrhea or stomach pain
burning when you urinate or urinating more often than normal
After starting BIMZELX, call your healthcare provider right away if you have any of the signs of infection listed above. Do not use BIMZELX if you have any signs of infection unless you are instructed to by your healthcare provider. See “What are the possible side effects of BIMZELX?” for more information about side effects.
What is BIMZELX?
BIMZELX is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet light alone or with pills (phototherapy).
It is not known if BIMZELX is safe and effective in children.
Before using BIMZELX, tell your healthcare provider about all of your medical conditions, including if you:
have any of the conditions or symptoms listed in the section “What is the most important information I should know about BIMZELX?”
have a history of depression, or suicidal thoughts or behavior
have liver problems
have inflammatory bowel disease (Crohn’s disease or ulcerative colitis)
have recently received or are scheduled to receive an immunization (vaccine). You should avoid receiving live vaccines during treatment with BIMZELX.
are pregnant or plan to become pregnant. It is not known if BIMZELX can harm your unborn baby.
If you become pregnant while taking BIMZELX, you are encouraged to enroll in the Pregnancy Registry, which is used to collect information about the health of you and your baby. Talk to your healthcare provider or call 1-877-311-8972 to enroll in this registry or visit http://mothertobaby.org/pregnancy-studies/.
are breastfeeding or plan to breastfeed. It is not known if BIMZELX passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with BIMZELX.
Tell your healthcare provider about all the medicines you take, including prescription and over the counter medicines, vitamins and herbal supplements.
What are the possible side effects of BIMZELX?
BIMZELX may cause serious side effects. See “What is important information I should know about BIMZELX?”
Elevated liver enzyme levels. Your healthcare provider will do blood tests to check your liver enzyme levels before starting treatment and during treatment with BIMZELX. Your healthcare provider may temporarily stop or permanently stop your treatment with BIMZELX if you develop liver problems. Call your healthcare provider right away if you develop any signs or symptoms of liver problems, including:
pain on the right side of your stomach-area
feeling very tired
loss of appetite
nausea and vomiting
itching
dark urine
light-colored stool
yellowing of your skin or the whites of your eyes
Inflammatory bowel disease. New cases of inflammatory bowel disease or “flare-ups” have happened with BIMZELX. If you have inflammatory bowel disease (Crohn’s disease or ulcerative colitis), tell your healthcare provider if you have worsening disease symptoms during treatment with BIMZELX or develop new or worsening signs of Crohn’s disease or ulcerative colitis.
The most common side effects of BIMZELX include:
upper respiratory tract infections
headache
Herpes Simplex infections (cold sores in or around the mouth)
small red bumps on your skin
feeling tired
fungal infections (oral thrush or infections in the mouth, throat, skin, nails, feet, or genitals)
pain, redness, or swelling at the injection site
stomach flu (gastroenteritis)
acne
These are not all of the possible side effects of BIMZELX. Call your doctor for medical advice about side effects.

Use BIMZELX exactly has your doctor tells you to use it.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

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For the full Prescribing Information and Medication Guide, please visit BIMZELX.com.

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All rights reserved. October 2023. US-P-BK-PSO-2300174